Education
| Ph.D. | Columbia University, Biological Sciences with Distinction |
May 2007 |
| M.Phil. | Columbia University, Biological Sciences | October 2005 |
| M.A. | Columbia University, Biological Sciences | October 2003 |
| B.S. | University of Wisconsin, Madison, Genetics with Highest Distinction (4.0 GPA) Degree completed in 3 years total |
May 2001 |
Research Experience
| Systems Improvement Lead, Computational Biology Platform Monsanto, St. Louis, MO |
2011 - present |
| Gene Regulation Lead, Gene Expression Technology Monsanto, Agracetus Campus, Middleton, WI |
2010 - 2011 |
| Computational Biologist, Gene Expression Technology Monsanto, Agracetus Campus, Middleton, WI |
2009 - 2010 |
| Genetics Fellow & Postdoctoral Research Associate Department of Genetics, Washington University School of Medicine, St. Louis, MO Discovering structurally defined cis-regulatory elements within mRNAs by integrative analysis of genomic sequence and functional genomics data. Advisor: Gary D. Stormo |
2007 - 2009 |
| Doctoral Student & Graduate Research Assistant Department of Biological Sciences, Columbia University, New York, NY Quantitative modeling of gene expression regulation by RNA-binding proteins and transcription factors in Saccharomyces cerevisiae. Advisor: Harmen J. Bussemaker |
2002 - 2007 |
| Rotation Student
Department of Biological Sciences, Columbia University, New York, NY Localization of Na+ channels on dendritic spines of neurons from mouse optical cortex. Advisor: Rafael Yuste |
2001 |
| Rotation Student Department of Biological Sciences, Columbia University, New York, NY Expression of Gene T07D1.3 in C. elegans Touch Receptor Neurons. Advisor: Martin Chalfie |
2001 |
| Laboratory Technician Comprehensive Cancer Center, University of Wisconsin, Madison, WI Drug testing on human prostate cancer cell lines. Employer: Ajit K. Verma |
2001 |
| Hilldale Undergraduate Research Fellow & Research Assistant Department of Botany, University of Wisconsin, Madison, WI Characterization of cyanobacterial homologs of the A. thaliana ETR1 ethylene-binding domain. Advisor: Anthony B. Bleecker |
1999 - 2001 |
| Summer Research Training Program Participant Department of Biochemistry and Biophysics, University of California, San Francisco, CA Cell cycle control and sister chromatid cohesion and separation in D. melanogaster. Advisor: Patrick H. O'Farrell |
2000 |
Teaching Experience
| Guest Lecturer Harmen Bussemaker's course on Bioinformatics of Gene Expression Regulation at Columbia University |
2004 - 2007 |
| Teaching Assistant Harmen Bussemaker's course on Bioinformatics of Gene Expression Regulation at Columbia University |
2003 |
| Teaching Assistant Martin Chalfie's course on Genetics at Columbia University |
2002 |
| Tutor Introductory Genetics, TRIO Tutoring Program University of Wisconsin, Madison |
2000 |
Awards & Fellowships
| Post Doctoral Fellow in Informatics Awarded by the PhRMA Foundation, Washington, DC |
2007 - 2009 |
| Genetics Fellow Awarded by the Department of Genetics, Washington University School of Medicine, St. Louis, MO |
2007 - 2009 |
| Young Investigator New York Academy of Sciences Update: profiles of promising researchers |
Nov., Dec. 2006 |
| Newberry Graduate Fellow Department of Biological Sciences, Columbia University, New York, NY |
2006 - 2007 |
| Sajovic Graduate Fellow Department of Biological Sciences, Columbia University, New York, NY |
2005 - 2006, 2002 - 2003 |
| Insight Award for poster presentation at the Conference on Research in Computational Molecular Biology (RECOMB) 2005. 1 of 2 awards out of 200 posters. |
2005 |
| Recipient of Departmental National Institutes of Health Training Grant Department of Biological Sciences, Columbia University, NY |
2003 - 2005 |
| Honorable Mention, Predoctoral Fellowship in Biological Sciences Howard Hughes Medical Institute |
2002 |
| Honorable Mention, Graduate Research Fellowship National Science Foundation |
2002 |
| Outstanding Senior Award College of Agricultural and Life Sciences, University of Wisconsin, Madison, WI |
2001 |
| Hilldale Undergraduate Research Fellow University of Wisconsin, Madison, WI |
2000 - 2001 |
| Summer Research Training Program Participant Department of Biochemistry and Biophysics, University of California, San Francisco, CA |
2000 |
Presentations
| RECOMB Satellite on Regulatory Genomics, Broad Institute, Cambridge, MA Discovering Structural Cis-Regulatory Elements by Modeling the Behaviors of mRNAs. |
Oct. 29-Nov. 2, 2008 Talk |
| Translational Control Meeting, Cold Spring Harbor Laboratories, Cold Spring Harbor, NY Discovering structural cis-regulatory elements in eukaryotic mRNAs predictive modeling of functional genomics data - Smaug, Vts1, and others. |
Sept. 3-7, 2008 Poster |
| Intelligent Systems for Molecular Biology (ISMB), Toronto, Canada Regulation of gene expression via mRNA secondary structure elements. |
July 19-23, 2008 Poster |
| Pacific Symposium on Biocomputing (PSB), Wailea, Maui, HI The Yeast Transfactome Database: a resource for exploring trans factor sequence specificities and post-translational regulatory activities. |
Jan. 3-7, 2007 Poster |
| Pacific Symposium on Biocomputing (PSB), Wailea, Maui, HI Comparing biophysical inference and information theory for explaining transcription factor-DNA interactions. |
Jan. 3-7, 2007 Abstract (Poster with Bussemaker) |
| Intelligent Systems for Molecular Biology (ISMB), Fortaleza, Brazil Statistical mechanical modeling of genome-wide transcription factor occupancy data by MatrixREDUCE. |
Aug. 8, 2006 Paper (Talk by Bussemaker) |
| Systems Biology Meeting, Cold Spring Harbor Laboratories, Cold Spring Harbor, NY Inferring Sequence Specificity, Condition-Specific Activity, and Functional Regulatory Targets of Yeast Transcription Factors by Integrative Modeling of mRNA Expression Data, ChIP-chip Data, and Genomic Sequence |
March 24, 2006 Poster |
| Systems Biology Meeting, Cold Spring Harbor Laboratories, Cold Spring Harbor, NY Quantifying the sequence specificity or transcription factors via statistical mechanical modeling of genome-wide occupancy data and structure-based prediction. |
March 24, 2006 Abstract (Talk by Bussemaker) |
| Eukaryotic mRNA Processing Meeting, Cold Spring Harbor Laboratories, Cold Spring Harbor, NY Profiling condition-specific, genome-wide regulation of mRNA stability in yeast. |
Aug. 24, 2005 Talk |
| Conference on Research in Computational Molecular Biology (RECOMB), Cambridge, MA Profiling condition-specific, genome-wide regulation of mRNA stability in yeast. |
May 14, 2005 Poster |
| Computational Biology and Bioinformatics Discussion Group, New York Academy of Sciences, New York, NY Profiling condition-specific, genome-wide regulation of mRNA stability in yeast. |
May 11, 2005 Talk |
Computer Proficiencies
Clojure, Perl, C, R, SQL, High performance computing, MPI, parallel programming, CGI web applications, Linux administration, Linux computer cluster design and maintenance
Laboratory Proficiencies
Standard molecular biology methods
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